FGF-23 (clone FG322-3), anti-human
€204.00
In stock
SKU
ARP-23-A0073
Catalog Number: 23-A0073
Size: 25 µg
Isotype: Mouse IgG1 kappa
Size: 25 µg
Isotype: Mouse IgG1 kappa
Decription:
FGF-23 is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) and of hyperphosphatemic familial tumoral calcinosis (HFTC).
Synonyms: Fibroblast Growth Factor 23, Tumor-derived Hypophosphatemia-inducing Factor
Clone: FG322-3
Isotype: Mouse IgG1 kappa
Immunogen: Recombinant human FGF-23.
Reactivity: human
Specificity: Recognizes human FGF-23. Does not cross-react with mouse FGF-23.
Form: Purified, in 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Applications:
ELISA: (direct and indirect: 1:2'000-1:5'000)
Immunohistochemistry: (paraffin sections (1:100-1:500))
Western Blot: (1:2'000-1:5'000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Working Dilution: Optimal conditions must be determined individually for each application.
Concentration: 1mg/ml
Storage: 2-8C immediate use, or -20C (aliquote)
FGF-23 is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) and of hyperphosphatemic familial tumoral calcinosis (HFTC).
Synonyms: Fibroblast Growth Factor 23, Tumor-derived Hypophosphatemia-inducing Factor
Clone: FG322-3
Isotype: Mouse IgG1 kappa
Immunogen: Recombinant human FGF-23.
Reactivity: human
Specificity: Recognizes human FGF-23. Does not cross-react with mouse FGF-23.
Form: Purified, in 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Applications:
ELISA: (direct and indirect: 1:2'000-1:5'000)
Immunohistochemistry: (paraffin sections (1:100-1:500))
Western Blot: (1:2'000-1:5'000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).
Working Dilution: Optimal conditions must be determined individually for each application.
Concentration: 1mg/ml
Storage: 2-8C immediate use, or -20C (aliquote)
| Is Featured? | No |
|---|
Write Your Own Review