FGF12 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [

Research Area: Cardiovascular, Signal Transduction

Synonyms:
EIEE47, FGF-12, Fgf12, FGF12, FGF12B, FHF-1, FHF1, Fibroblast growth factor 12, Fibroblast growth factor 12B, Fibroblast growth factor FGF 12b, Fibroblast growth factor homologous factor 1, Myocyte activating factor, Myocyte-activating factor

Immunogen: Recombinant protein of human FGF12

Swissprot: P61328
Gene Accession: BC022524

Calculated MW: 20 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-22355/sc-16809/sc-292583