FGF2 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

Research Area: Cancer, Cardiovascular, Developmental Biology, Neuroscience, Signal Transduction, Stem Cells

Synonyms:
Basic fibroblast growth factor, Basic fibroblast growth factor bFGF, BFGF, FGF 2, FGF B, FGF-2, Fgf2, FGF2 basic, FGF2, FGFB, Fibroblast growth factor 2 (basic), Fibroblast growth factor 2, Fibroblast growth factor, basic, HBGF 2, HBGF-2, HBGF2, HBGH 2, HBGH2, Heparin binding growth factor 2 precursor, Heparin-binding growth factor 2, Prostatropin

Immunogen: Synthetic peptide of human FGF2

Swissprot: P09038
Gene Accession: NP_001997

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-1360/sc-1390/sc-79/sc-7911