FGF2 Polyclonal Antibody
€0.00
In stock
SKU
E-AB-40357
Catalog Number: E-AB-40357
Isotype: Rabbit IgG
Reactivity: mouse
Applications: IHC
Datasheet, Questions? Contact us!
Isotype: Rabbit IgG
Reactivity: mouse
Applications: IHC
Datasheet, Questions? Contact us!
Background:
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Research Area: Cancer, Cardiovascular, Signal Transduction, Neuroscience, Stem Cells, Developmental Biology
Synonyms:
Basic fibroblast growth factor, Basic fibroblast growth factor bFGF, BFGF, FGF 2, FGF B, FGF-2, Fgf2, FGF2 basic, FGF2, FGFB, Fibroblast growth factor 2 (basic), Fibroblast growth factor 2, Fibroblast growth factor, basic, HBGF 2, HBGF-2, HBGF2, HBGH 2, HBGH2, Heparin binding growth factor 2 precursor, Heparin-binding growth factor 2, Prostatropin
Immunogen: Recombinant Mouse Fibroblast growth factor 2 protein
Swissprot: P15655
Gene ID: 14173
Purification Method: Antigen Affinity Purification
Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3
Concentration: 0.7 mg/mL
Dilution: IHC 1:50-1:200
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Research Area: Cancer, Cardiovascular, Signal Transduction, Neuroscience, Stem Cells, Developmental Biology
Synonyms:
Basic fibroblast growth factor, Basic fibroblast growth factor bFGF, BFGF, FGF 2, FGF B, FGF-2, Fgf2, FGF2 basic, FGF2, FGFB, Fibroblast growth factor 2 (basic), Fibroblast growth factor 2, Fibroblast growth factor, basic, HBGF 2, HBGF-2, HBGF2, HBGH 2, HBGH2, Heparin binding growth factor 2 precursor, Heparin-binding growth factor 2, Prostatropin
Immunogen: Recombinant Mouse Fibroblast growth factor 2 protein
Swissprot: P15655
Gene ID: 14173
Purification Method: Antigen Affinity Purification
Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3
Concentration: 0.7 mg/mL
Dilution: IHC 1:50-1:200
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
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