FGF2 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

Research Area: Cancer, Cardiovascular, Developmental Biology, Neuroscience, Signal Transduction, Stem Cells

Synonyms:
BFGF, FGF-2, FGFB, HBGF-2, Basic FGF, FGF2

Immunogen: Recombinant fusion protein of human FGF2 (NP_001997.5).

Swissprot: P09038
Gene ID: 2247

Calculated MW: 17 kDa/21 kDa/22 kDa/30 kDa
Observed MW: 20 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.