FGF21 polyclonal, anti-human, mouse, rat

Background:
Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithe-lial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10-FGF-23. Members of the FGF family share 30-55% amino acid sequence identity and similar gene structure and are capable of transforming cultured cells when overexpressed in transfected cells. Cellular receptors for FGFs are members of a second multigene family including four tyrosine kinases, designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.

Alternative Name:
FGF-21, FGF 21, FGF-21, Fgf21, FGF21, FGFL, Fibroblast growth factor 21, PRO10196, UNQ3115,

Application Dilution:
WB:1:1,000-1:5,000
IHC:1:50-1:200

Specificity: FGF21 polyclonal antibody detects endogenous levels of FGF21 protein.

Immunogen:
recombinant protein

MW: 22 kDa

Swiss-Prot: Q9NSA1(Human) Q9JJN1(Mouse) EntrezGene:170580 (Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.