FGF4 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.

Research Area: Cancer, Cardiovascular, Signal Transduction

Synonyms:
FGF-4, Fgf4, FGF4, Fibroblast growth factor 4, fibroblast growth factor 4 splice isoform, HBGF-4, HBGF4, Heparin secretory-transforming protein 1, Heparin-binding growth factor 4, Hst, HST-1, HST1, HSTF-1, HSTF1, Human stomach cancer transforming factor from FGF related oncogene, K FGF, Kaposi Sarcoma Oncogene, KFGF, KS3, Oncogene HST, Transforming protein KS3

Immunogen: Synthetic peptide of human FGF4

Swissprot: P08620
Gene Accession: NP_001998

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: IHC 1:50-1:150

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-1361