FGF8 antibody (clone 3B10), anti-human
€435.00
In stock
SKU
AC-AT2035a
Catalog Number: AC-AT2035a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: E
Request Information AC-AT2035a">Request Information
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: E
Request Information AC-AT2035a">Request Information
Background:
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants.
Other Names:
Fibroblast growth factor 8, FGF-8, Androgen-induced growth factor, AIGF, Heparin-binding growth factor 8, HBGF-8, FGF8, AIGF
Antigen Type:
Recombinant Protein
Gene Name: FGF8
Gene ID: 2253
NCBI Accession: NP_006110.1;NP_149353.1;NP_149354.1;NP_149355.1
Primary Accession: P55075
Other Accession: NM_033164
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants.
Other Names:
Fibroblast growth factor 8, FGF-8, Androgen-induced growth factor, AIGF, Heparin-binding growth factor 8, HBGF-8, FGF8, AIGF
Antigen Type:
Recombinant Protein
Gene Name: FGF8
Gene ID: 2253
NCBI Accession: NP_006110.1;NP_149353.1;NP_149354.1;NP_149355.1
Primary Accession: P55075
Other Accession: NM_033164
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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