FGFR1 polyclonal (Y154), anti-human
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In stock
SKU
AC-AP7636h
Catalog Number: AC-AP7636h
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB12705
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB12705
Applications: WB
Datasheet
Request Information
Background:
FGFR1 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene can lead to Pfeiffer syndrome and Jackson-Weiss syndrome.
Other Names:
Fibroblast growth factor receptor 1, FGFR-1, Basic fibroblast growth factor receptor 1, BFGFR, bFGF-R-1, Fms-like tyrosine kinase 2, FLT-2, N-sam, Proto-oncogene c-Fgr, CD331, FGFR1, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR
Target/Specificity:
This FGFR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-161 amino acids from human FGFR1.
Antigen Region:
132-161
Antigen Type: Synthetic Peptide
Gene Name: FGFR1
Gene ID: 2260
Primary Accession: P11362
NCBI Accession: NP_001167534.1;NP_001167535.1;NP_001167536.1;NP_001167537.1;NP_001167538.1;NP_056934.2;NP_075593.1;NP_075594.1;NP_075598.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
FGFR1 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene can lead to Pfeiffer syndrome and Jackson-Weiss syndrome.
Other Names:
Fibroblast growth factor receptor 1, FGFR-1, Basic fibroblast growth factor receptor 1, BFGFR, bFGF-R-1, Fms-like tyrosine kinase 2, FLT-2, N-sam, Proto-oncogene c-Fgr, CD331, FGFR1, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR
Target/Specificity:
This FGFR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-161 amino acids from human FGFR1.
Antigen Region:
132-161
Antigen Type: Synthetic Peptide
Gene Name: FGFR1
Gene ID: 2260
Primary Accession: P11362
NCBI Accession: NP_001167534.1;NP_001167535.1;NP_001167536.1;NP_001167537.1;NP_001167538.1;NP_056934.2;NP_075593.1;NP_075594.1;NP_075598.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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