FGG antibody (clone 1F2), anti-human
€435.00
In stock
SKU
AC-AT2039a
Catalog Number: AC-AT2039a
Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IHC, E
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Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IHC, E
Request Information AC-AT2039a">Request Information
Background:
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
Other Names:
Fibrinogen gamma chain, FGG
Antigen Type:
Recombinant Protein
Gene Name: FGG
Gene ID: 2266
NCBI Accession: NP_000500.2;NP_068656.2
Primary Accession: P02679
Other Accession: BC007044
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
Other Names:
Fibrinogen gamma chain, FGG
Antigen Type:
Recombinant Protein
Gene Name: FGG
Gene ID: 2266
NCBI Accession: NP_000500.2;NP_068656.2
Primary Accession: P02679
Other Accession: BC007044
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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