FGG monoclonal (Ascites), anti-human
€470.00
In stock
SKU
AC-AM2135a
Catalog Number: AC-AM2135a
Size: 100 µl
Isotype: mouse IgG1
Clone Name: 546CT11.4.3
Applications: WB
Datasheet
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Size: 100 µl
Isotype: mouse IgG1
Clone Name: 546CT11.4.3
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
Other Names:
Fibrinogen gamma chain, FGG
Target/Specificity:
This FGG antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 417-445 amino acids from human FGG .
Antigen Region:
417-445
Antigen Type: Synthetic Peptide
Gene Name: FGG
Gene ID: 2266
Primary Accession: P02679
NCBI Accession: NP_000500.2;NP_068656.2
Other Accession: NP_068656
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
Other Names:
Fibrinogen gamma chain, FGG
Target/Specificity:
This FGG antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 417-445 amino acids from human FGG .
Antigen Region:
417-445
Antigen Type: Synthetic Peptide
Gene Name: FGG
Gene ID: 2266
Primary Accession: P02679
NCBI Accession: NP_000500.2;NP_068656.2
Other Accession: NP_068656
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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