FGG Polyclonal Antibody

Background:
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms.

Research Area: Cardiovascular

Synonyms:
FGG, Fibrinogen gamma chain, Fibrinogen gamma polypeptide

Immunogen: Recombinant Mouse Fibrinogen gamma chain protein

Swissprot: Q8VCM7
Gene ID: 99571

Calculated MW: 49 kDa
Observed MW: 49 kDa

Purification Method: Antigen Affinity Purification

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: WB 1:1000-1:3000 IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.