FGG polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP7325a
Catalog Number: AC-AP7325a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18713
Applications: WB, IF, FC
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18713
Applications: WB, IF, FC
Datasheet
Request Information
Background:
FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this protein lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia.
Other Names:
Fibrinogen gamma chain, FGG
Target/Specificity:
This FGG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-118 amino acids from the N-terminal region of human FGG.
Antigen Region:
91-118
Antigen Type: Synthetic Peptide
Gene Name: FGG
Gene ID: 2266
Primary Accession: P02679
NCBI Accession: NP_000500.2;NP_068656.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this protein lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia.
Other Names:
Fibrinogen gamma chain, FGG
Target/Specificity:
This FGG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-118 amino acids from the N-terminal region of human FGG.
Antigen Region:
91-118
Antigen Type: Synthetic Peptide
Gene Name: FGG
Gene ID: 2266
Primary Accession: P02679
NCBI Accession: NP_000500.2;NP_068656.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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