FGR polyclonal, anti-human
€388.00
In stock
SKU
BS72325
Background:
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alternative Name:
c-fgr,c-src2,p55-Fgr,p55c-fgr,p58-Fgr,p58c-fgr,SRC2
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: FGR polyclonal antibody detects endogenous levels of FGR protein.
Immunogen:
A synthetic peptide of human FGR
MW: ~ 55 kDa
Swis Prot.: P09769
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alternative Name:
c-fgr,c-src2,p55-Fgr,p55c-fgr,p58-Fgr,p58c-fgr,SRC2
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: FGR polyclonal antibody detects endogenous levels of FGR protein.
Immunogen:
A synthetic peptide of human FGR
MW: ~ 55 kDa
Swis Prot.: P09769
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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