FH/Fumarase (clone 7F1), anti-human, mouse, rat

Background:
Fumarase (FH) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate. Fumarase comes in two forms: mitochondrial and cytosolic. The mitochondrial isoenzyme is involved in the Krebs Cycle (also known as the Tricarboxylic Acid Cycle [TCA] or the Citric Acid Cycle), and the cytosolic isoenzyme is involved in the metabolism of amino acids and fumarate. Subcellular localization is established by the presence of a signal sequence on the amino terminus in the mitochondrial form, while subcellular localization in the cytosolic form is established by the absence of the signal sequence found in the mitochondrial variety.

Synonyms: FMRD, HLRCC, LRCC, MCL, MCUL1

Cellular Location: Cytoplasm Mitochondrion

Immunogen:
Synthetic Peptide

Gene Symbol: FH/Fumarase

Gene ID: 2271

Swiss prot: P07954

Calculated MW: 50kDa

Recommended dilution:
WB 1:3000, IF 1:100-200,

Purity:
Saturated ammonium sulfate precipitation

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.