FH/Fumarase Rabbit pAb

Background:
Fumarase (FH) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate in the mitochondria. Fumarase deficiency is caused by a mutation in the fumarase gene in humans. Fumarase deficiency is one of the few known deficiencies of the Krebs cycle or tricarboxylic acid cycle, the main enzymatic pathway of cellular aerobic respiration. 

Specificity: Human

Alternative Names:
Fumarase, fumarate hydratase, HLRCC, LRCC, MCL, MCUL1

Immunogen: Recombinant Protein

Isotype: Rabbit Polyclonal IgG

Concentration: 1mg/ml

Recommended dilutions: WB 1:1,000

Observed band: 50kDa

GeneID: 2271

Swiss-Prot No.: P07954

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Store at -20°C. Avoid repeated freeze-thaw cycles.

NOTE: For Research Use Only