FHIT antibody (clone 1000), anti-human
€435.00
In stock
SKU
AC-AT2046a
Catalog Number: AC-AT2046a
Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, E
Request Information AC-AT2046a">Request Information
Background:
This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.
Other Names:
Bis(5'-adenosyl)-triphosphatase, AP3A hydrolase, AP3Aase, Diadenosine 5',5'''-P1,P3-triphosphate hydrolase, Dinucleosidetriphosphatase, Fragile histidine triad protein, FHIT
Antigen Type:
Recombinant Protein
Gene Name: FHIT
Gene ID: 2272
NCBI Accession: NP_001159715.1;NP_002003.1
Primary Accession: P49789
Other Accession: BC032336
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.
Other Names:
Bis(5'-adenosyl)-triphosphatase, AP3A hydrolase, AP3Aase, Diadenosine 5',5'''-P1,P3-triphosphate hydrolase, Dinucleosidetriphosphatase, Fragile histidine triad protein, FHIT
Antigen Type:
Recombinant Protein
Gene Name: FHIT
Gene ID: 2272
NCBI Accession: NP_001159715.1;NP_002003.1
Primary Accession: P49789
Other Accession: BC032336
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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