FHIT polyclonal, anti-human

Background:
This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.

Synonyms: AP3Aase, FRA3B, fragile histidine triad

Cellular Location: Cytoplasm Nucleus

Immunogen:
A synthetic peptide of human FHIT

Gene Symbol: FHIT

Gene ID: 2272

Swiss prot: P49789

Calculated MW: 17kDa

Recommended dilution:
IHC 1:100-300

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.