FHL2 Polyclonal Antibody

Background:
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants encoding different isoforms have been identified.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
FHL2, AAG11, DRAL, FHL-2, SLIM-3, SLIM3

Immunogen: Recombinant fusion protein of human FHL2 (NP_001034581.1).

Swissprot: Q14192
Gene ID: 2274

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.