FIBB polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP6517a
Catalog Number: AC-AP6517a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19512
Applications: IHC-P, FC, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19512
Applications: IHC-P, FC, WB
Datasheet
Request Information
Background:
FIBB is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
Other Names:
Fibrinogen beta chain, Fibrinopeptide B, Fibrinogen beta chain, FGB
Target/Specificity:
This FIBB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human FIBB.
Antigen Region:
29-58
Antigen Type: Synthetic Peptide
Gene Name: FGB
Gene ID: 2244
Primary Accession: P02675
NCBI Accession: NP_001171670.1;NP_005132.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
FIBB is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
Other Names:
Fibrinogen beta chain, Fibrinopeptide B, Fibrinogen beta chain, FGB
Target/Specificity:
This FIBB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human FIBB.
Antigen Region:
29-58
Antigen Type: Synthetic Peptide
Gene Name: FGB
Gene ID: 2244
Primary Accession: P02675
NCBI Accession: NP_001171670.1;NP_005132.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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