FIBG polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP6583B
Catalog Number: AC-AP6583B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19515
Applications: IHC-P, IF, WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19515
Applications: IHC-P, IF, WB
Datasheet
Request Information
Background:
FIBG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia.
Other Names:
Fibrinogen gamma chain, FGG
Target/Specificity:
This FIBG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 420-449 amino acids from the C-terminal region of human FIBG.
Antigen Region:
420-449
Antigen Type: Synthetic Peptide
Gene Name: FGG
Gene ID: 2266
Primary Accession: P02679
NCBI Accession: NP_000500.2;NP_068656.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
FIBG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia.
Other Names:
Fibrinogen gamma chain, FGG
Target/Specificity:
This FIBG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 420-449 amino acids from the C-terminal region of human FIBG.
Antigen Region:
420-449
Antigen Type: Synthetic Peptide
Gene Name: FGG
Gene ID: 2266
Primary Accession: P02679
NCBI Accession: NP_000500.2;NP_068656.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
|---|
Write Your Own Review