Fibrinogen β / FGB polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6607
Background:
Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i.e., the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types.
Alternative Name:
Fibrinogen beta chain, Fibrinopeptide B, Fibrinogen beta chain, FGB, Fibrinogen β, Fibrinogenβ, Fibrinogen-β
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: FGB polyclonal antibody detects endogenous levels of FGB protein.
Immunogen:
Recombinant full length Human Fibrinogen β.
MW: ~ 56 kDa
Swis Prot.: P02675
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i.e., the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types.
Alternative Name:
Fibrinogen beta chain, Fibrinopeptide B, Fibrinogen beta chain, FGB, Fibrinogen β, Fibrinogenβ, Fibrinogen-β
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: FGB polyclonal antibody detects endogenous levels of FGB protein.
Immunogen:
Recombinant full length Human Fibrinogen β.
MW: ~ 56 kDa
Swis Prot.: P02675
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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