Fibronectin polyclonal, anti-human

Background:
Fibronectin is an extracellular matrix glycoprotein present on most cell surfaces, in extracellular fluids and in plasma. A high molecular weight heterodimeric protein, it was originally discovered as a protein missing from the surfaces of virus-transformed cells, and it has been shown to be involved in various functions including cell adhesion, cell motility and wound healing. Alternative splicing and glycosylation give rise to several different forms of Fibronectin, some of which exhibit restricted tissue distribution or association with malignancies. It has been shown that Myofibroblast phenotype formation correlates with the occurrence of glycosylated Fibronectin and Fibronectin splice variants in Dupuytren's disease.

Alternative Name:
FN, CIG, FN1, CIG, Cold insoluble globulin, Cold-insoluble globulin, DKFZp686F10164, DKFZp686H0342, DKFZp686I1370, DKFZp686O13149, ED B, Fibronectin 1, FINC, FINC, FN, FN1, FNZ, GFND, GFND2, LETS, Migration stimulating factor, MSF, Ugl-Y3,

Application Dilution:
WB:1:1,000
ICC:1:100-1:500
IHC:1:50-1:200

Specificity: Fibronectin polyclonal antibody detects endogenous levels of Fibronectin protein.

Immunogen:
recombinant protein

MW: 263 kDa

Swiss-Prot: P02751(Human)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.