Fibronectin polyclonal, anti-human, mouse, rat, dog, pig , bovine

Protein Family: CAM Ligands; Receptors and Channels; Cell Adhesion Molecules

Pathway and Disease: Cancers, Signaling Molecules and Interaction, Cell Motility, Cell Communications

Description:
Fibronectin is an adhesive glycoprotein with a molecular mass of 440 kDa. It is believed to be important for the formation of a provisional matrix that promotes cell adhesion and migration during wound healing. Its age-dependent increase in plasma and tissues may be accompanied in pathological states, especially in tumor growth, by its proteolytic breakdown by a number of neutral proteases. It has also shown that several of its proteolytic breakdown products exhibit unexpected and mostly harmful biological activities.

Alternate Names: FN, Cold-insoluble globulin, CIG, Fibronectin

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: P02751

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human fibronectin.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1 mg/ml BSA, 25% glycerol with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.