Fibronectin Polyclonal Antibody

Background:
This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined.

Research Area: Cancer, Cardiovascular, Developmental Biology, Signal Transduction, Stem Cells

Synonyms:
FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF, fibronectin

Immunogen: Recombinant fusion protein of human Fibronectin (NP_002017.1).

Swissprot: P02751
Gene ID: 2335

Calculated MW: 71-73 kDa/221-272 kDa
Observed MW: 290 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:1000 IHC 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.