Fibulin-2 (E279) polyclonal, anti-human
€305.00
In stock
SKU
BS9147
Background:
Fibulin-1 and Fibulin-2 associate with Fibronectin and other extracellular matrix proteins. In bone marrow, Fibulin-1 and Fibulin-2 bind to Fibronectin in the adherent layer. Fibulin-2 binds to the lectin domains of extracellular matrix proteins aggrecan, versican and brevican. Fibulin-2 is abundantly expressed in heart, placenta and ovarian tissue, where it localizes to basement membranes and connective tissue compartments. In mice, differential Fibulin-2 gene expression correlates with the early phase of diabetic kidneys and glomerulosclerosis. The gene encoding human Fibulin-2 maps to chromosome 3p25.1.
Alternative Name:
Fbln2, FBLN2, FIBL-2, Fibulin-2,
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: Fibulin-2 (E279) polyclonal antibody detects endogenous levels of Fibulin-2 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 249-300 of Human Fibulin-2.
MW: ~ 127 kDa
Swis Prot.: P98095
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Fibulin-1 and Fibulin-2 associate with Fibronectin and other extracellular matrix proteins. In bone marrow, Fibulin-1 and Fibulin-2 bind to Fibronectin in the adherent layer. Fibulin-2 binds to the lectin domains of extracellular matrix proteins aggrecan, versican and brevican. Fibulin-2 is abundantly expressed in heart, placenta and ovarian tissue, where it localizes to basement membranes and connective tissue compartments. In mice, differential Fibulin-2 gene expression correlates with the early phase of diabetic kidneys and glomerulosclerosis. The gene encoding human Fibulin-2 maps to chromosome 3p25.1.
Alternative Name:
Fbln2, FBLN2, FIBL-2, Fibulin-2,
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: Fibulin-2 (E279) polyclonal antibody detects endogenous levels of Fibulin-2 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 249-300 of Human Fibulin-2.
MW: ~ 127 kDa
Swis Prot.: P98095
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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