FIG4 polyclonal (C-term), anti-human, mouse
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In stock
SKU
AC-AP18145b
Catalog Number: AC-AP18145b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB24204
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB24204
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J.
Other Names:
Polyphosphoinositide phosphatase, 313-, Phosphatidylinositol 3,5-bisphosphate 5-phosphatase, SAC domain-containing protein 3, FIG4, KIAA0274, SAC3
Target/Specificity:
This FIG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 846-874 amino acids from the C-terminal region of human FIG4.
Antigen Region:
846-874
Antigen Type: Synthetic Peptide
Gene Name: FIG4 (HGNC:16873)
Gene ID: 9896
Primary Accession: Q92562
NCBI Accession: NP_055660.1
Other Accession: Q91WF7; NP_055660.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J.
Other Names:
Polyphosphoinositide phosphatase, 313-, Phosphatidylinositol 3,5-bisphosphate 5-phosphatase, SAC domain-containing protein 3, FIG4, KIAA0274, SAC3
Target/Specificity:
This FIG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 846-874 amino acids from the C-terminal region of human FIG4.
Antigen Region:
846-874
Antigen Type: Synthetic Peptide
Gene Name: FIG4 (HGNC:16873)
Gene ID: 9896
Primary Accession: Q92562
NCBI Accession: NP_055660.1
Other Accession: Q91WF7; NP_055660.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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