FILA2 Rabbit polyclonal antibody, anti-human, mouse

Background:
The filaggrin-like protein encoded by this gene is upregulated by calcium| proteolyzed by calpain 1| and is involved in epithelial homeostasis. The encoded protein is required for proper cornification in skin| with defects in this gene being associated with skin diseases. This protein also has a function in skin barrier protection. In fact| in addition to providing a physical barrier| C-terminal fragments of this protein display antimicrobial activity against P. aeruginosa.

Research Area: Signal transduction

Synonyms: FILA2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year