Filaggrin polyclonal, anti-human

Quantity: 100 µg

Background:
In humans, profillagrin is encoded by the FLG gene, which is part of the S100 fused-type protein (SFTP) family within the epidermal differentiation complex on chromosome 1q21. The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.

Description:
Rabbit IgG polyclonal antibody for Filaggrin (FLG) detection. Tested with WB, IHC-P in Human.

Synonyms:
Epidermal filaggrin antibody, FILA_HUMAN antibody, Filaggrin antibody, Filaggrin precursor antibody, Fillagrin antibody, FLG antibody, Profilaggrin antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E. coli-derived human Filaggrin recombinant protein (Position: M1-R261).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.