FIS1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7881
Background:
Fis1 localizes to the outer mitochondrial membrane and, along with dynamin-related protein (Drp1), participates in mitochondrial fission. Fission and fusion mechanisms regulate mitochondrial morphology within the cell. Fission frequency is determined by the level of Fis1 molecules at the mitochondrial surface. Fis1 contains a C-terminal domain, which is required for mitochondrial localization, and an N-terminal domain, which is necessary for mitochondrial fission. Fragmentation of the mitochondrial network by Fis1 leads to cytochrome c release and apoptosis. The mitochondrial fission mechanisms may be involved in positively and negatively regulating apoptosis.
Alternative Name:
CGI 135, CGI135, FIS 1, FIS1, Fis1 homolog, FIS1, S. cerevisiae, homolog of, FIS1_HUMAN, Fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae), Fission 1 (mitochondrial outer membrane) homolog (yeast), Fission 1 (mitochondrial outer membrane) homolog, Fission 1 homolog, H NH0132A01.6, hFis 1, hFis1, Mitochondrial fission 1 protein, Tetratricopeptide repeat domain 11, Tetratricopeptide repeat protein 11, TPR repeat protein 11, TTC 11,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: FIS1 polyclonal antibody detects endogenous levels of FIS1 protein.
Immunogen:
Recombinant full length Human FIS1.
MW: ~ 17 kDa
Swis Prot.: Q9Y3D6
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Fis1 localizes to the outer mitochondrial membrane and, along with dynamin-related protein (Drp1), participates in mitochondrial fission. Fission and fusion mechanisms regulate mitochondrial morphology within the cell. Fission frequency is determined by the level of Fis1 molecules at the mitochondrial surface. Fis1 contains a C-terminal domain, which is required for mitochondrial localization, and an N-terminal domain, which is necessary for mitochondrial fission. Fragmentation of the mitochondrial network by Fis1 leads to cytochrome c release and apoptosis. The mitochondrial fission mechanisms may be involved in positively and negatively regulating apoptosis.
Alternative Name:
CGI 135, CGI135, FIS 1, FIS1, Fis1 homolog, FIS1, S. cerevisiae, homolog of, FIS1_HUMAN, Fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae), Fission 1 (mitochondrial outer membrane) homolog (yeast), Fission 1 (mitochondrial outer membrane) homolog, Fission 1 homolog, H NH0132A01.6, hFis 1, hFis1, Mitochondrial fission 1 protein, Tetratricopeptide repeat domain 11, Tetratricopeptide repeat protein 11, TPR repeat protein 11, TTC 11,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: FIS1 polyclonal antibody detects endogenous levels of FIS1 protein.
Immunogen:
Recombinant full length Human FIS1.
MW: ~ 17 kDa
Swis Prot.: Q9Y3D6
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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