FKBP1A polyclonal (Center), anti-human, mouse, rat

FKBP1A polyclonal (Center), anti-human, mouse, rat

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In stock
SKU
AC-AP21438c
Catalog Number: AC-AP21438c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB49821
Applications: WB
Datasheet

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Background:
Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Other Names:
Peptidyl-prolyl cis-trans isomerase FKBP1A, PPIase FKBP1A, 12 kDa FK506-binding protein, 12 kDa FKBP, FKBP-12, Calstabin-1, FK506-binding protein 1A, FKBP-1A, Immunophilin FKBP12, Rotamase, FKBP1A, FKBP1, FKBP12

Target/Specificity:
This FKBP1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 34-68 amino acids from the Central region of human FKBP1A.

Gene Name: FKBP1A
Gene ID: 2280
Primary Accession: P62942
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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