FKBP1B antibody (clone 4H5-1B6), anti-human
€435.00
In stock
SKU
AC-AT2056a
Catalog Number: AC-AT2056a
Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB
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Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB
Request Information AC-AT2056a">Request Information
Background:
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms.
Other Names:
Peptidyl-prolyl cis-trans isomerase FKBP1B, PPIase FKBP1B, 126 kDa FK506-binding protein, 126 kDa FKBP, FKBP-126, FK506-binding protein 1B, FKBP-1B, Immunophilin FKBP126, Rotamase, h-FKBP-12, FKBP1B, FKBP126, FKBP1L, FKBP9, OTK4
Antigen Type:
Recombinant Protein
Gene Name: FKBP1B (HGNC:3712)
Gene ID: 2281
NCBI Accession: NP_004107.1;NP_473374.1
Primary Accession: P68106
Other Accession: BC002614
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms.
Other Names:
Peptidyl-prolyl cis-trans isomerase FKBP1B, PPIase FKBP1B, 126 kDa FK506-binding protein, 126 kDa FKBP, FKBP-126, FK506-binding protein 1B, FKBP-1B, Immunophilin FKBP126, Rotamase, h-FKBP-12, FKBP1B, FKBP126, FKBP1L, FKBP9, OTK4
Antigen Type:
Recombinant Protein
Gene Name: FKBP1B (HGNC:3712)
Gene ID: 2281
NCBI Accession: NP_004107.1;NP_473374.1
Primary Accession: P68106
Other Accession: BC002614
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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