FKBP3 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
FKBP3, FKBP-25, FKBP-3, FKBP25, PPIase

Immunogen: Recombinant fusion protein of human FKBP3 (NP_002004.1).

Swissprot: Q00688
Gene ID: 2287

Calculated MW: 25 kDa
Observed MW: 30 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.