FKBP5 antibody (clone 3D1-1B10), anti-human
€435.00
In stock
SKU
AC-AT2058a
Catalog Number: AC-AT2058a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IF, E
Request Information AC-AT2058a">Request Information
Background:
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.
Other Names:
Peptidyl-prolyl cis-trans isomerase FKBP5, PPIase FKBP5, 51 kDa FK506-binding protein, 51 kDa FKBP, FKBP-51, 54 kDa progesterone receptor-associated immunophilin, Androgen-regulated protein 6, FF1 antigen, FK506-binding protein 5, FKBP-5, FKBP54, p54, HSP90-binding immunophilin, Rotamase, FKBP5, AIG6, FKBP51
Antigen Type:
Recombinant Protein
Gene Name: FKBP5
Gene ID: 2289
NCBI Accession: NP_001139247.1;NP_001139248.1;NP_001139249.1;NP_004108.1
Primary Accession: Q13451
Other Accession: BC042605
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.
Other Names:
Peptidyl-prolyl cis-trans isomerase FKBP5, PPIase FKBP5, 51 kDa FK506-binding protein, 51 kDa FKBP, FKBP-51, 54 kDa progesterone receptor-associated immunophilin, Androgen-regulated protein 6, FF1 antigen, FK506-binding protein 5, FKBP-5, FKBP54, p54, HSP90-binding immunophilin, Rotamase, FKBP5, AIG6, FKBP51
Antigen Type:
Recombinant Protein
Gene Name: FKBP5
Gene ID: 2289
NCBI Accession: NP_001139247.1;NP_001139248.1;NP_001139249.1;NP_004108.1
Primary Accession: Q13451
Other Accession: BC042605
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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