FKBP5 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS72339
Background:
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.
Alternative Name:
AIG6,FKBP51,FKBP54,P54,PPIase,Ptg-10
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: FKBP5 polyclonal antibody detects endogenous levels of FKBP5 protein.
Immunogen:
Recombinant protein of human FKBP5
MW: ~ 51 kDa
Swis Prot.: Q13451
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.
Alternative Name:
AIG6,FKBP51,FKBP54,P54,PPIase,Ptg-10
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: FKBP5 polyclonal antibody detects endogenous levels of FKBP5 protein.
Immunogen:
Recombinant protein of human FKBP5
MW: ~ 51 kDa
Swis Prot.: Q13451
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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