FKBP5 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Immunology, Signal transduction

Synonyms:
51 kDa FK506 binding protein 5, 51 kDa FK506 binding protein, 51 kDa FK506-binding protein, 51 kDa FKBP, 54 kDa progesterone receptor associated immunophilin, 54 kDa progesterone receptor-associated immunophilin, AIG 6, AIG6, Androgen regulated protein 6, Androgen-regulated protein 6, FF1 antigen, FK506 binding protein 5, FK506-binding protein 5, FKBP 5, FKBP 51, FKBP 54, FKBP-5, FKBP-51, FKBP5, FKBP5, FKBP54, HSP90 binding immunophilin, HSP90-binding immunophilin, MGC111006, OTTHUMP00000016268, P54, Peptidyl prolyl cis trans isomerase, Peptidyl-prolyl cis-trans isomerase FKBP5, Peptidylprolyl cis trans isomerase, PPIase, PPIase FKBP5, Ptg 10, Ptg10, Rotamase, T cell FK506 binding protein

Immunogen: Synthetic peptide of human FKBP5

Swissprot: Q13451
Gene Accession: NP004108

Calculated MW: 51 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.5 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.