FKBPL rabbit polyclonal, anti-human, mouse, rat

Backgroud: The protein encoded by this gene has similarity to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The encoded protein is thought to have a potential role in the induced radioresistance. Also it appears to have some involvement in the control of the cell cycle. [provided by RefSeq, Jul 2008],function:May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 3 TPR repeats.,subunit:Forms a ternary complex with CDKN1A/p21 and HSP90AB1/Hsp90.,tissue specificity:Ubiquitously expressed with higher levels in testis.,

Synonyms: FKBPL, DIR1, NG7, FK506-binding protein-like, WAF-1/CIP1 stabilizing protein 39, WISp39

Gene Name: FKBPL

Gene ID: 63943

SwissProt ID: Q9UIM3

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.