FLAP / ALOX5AP (internal) polyclonal, anti-human

Background:
This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.

Other Names:
Arachidonate 5-lipoxygenase-activating protein, FLAP, MK-886-binding protein, ALOX5AP, FLAP

Antigen Types:
Synthetic Peptide

Gene Name:
ALOX5AP
Gene ID:
241
Primary Accession: P20292
Other Accession: NP_001620;241;