FLCN polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP8658c
Catalog Number: AC-AP8658c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB20959
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB20959
Applications: IHC-P, WB
Datasheet
Request Information
Background:
FLCN may play a role in the pathogenesis of an uncommon form of kidney cancer through its association with an inherited disorder of the hair follicle (fibrofolliculomas). FLCN may be a tumor suppressor. May be involved in colorectal tumorigenesis. It may be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways.
Other Names:
Folliculin, BHD skin lesion fibrofolliculoma protein, Birt-Hogg-Dube syndrome protein, FLCN, BHD
Target/Specificity:
This FLCN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-354 amino acids from the Central region of human FLCN.
Antigen Region:
325-354
Antigen Type: Synthetic Peptide
Gene Name: FLCN {ECO:0000303|PubMed:15657874, ECO:0000312|HGNC:HGNC:27310}
Gene ID: 201163
Primary Accession: Q8NFG4
NCBI Accession: NP_653207.1;NP_659434.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
FLCN may play a role in the pathogenesis of an uncommon form of kidney cancer through its association with an inherited disorder of the hair follicle (fibrofolliculomas). FLCN may be a tumor suppressor. May be involved in colorectal tumorigenesis. It may be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways.
Other Names:
Folliculin, BHD skin lesion fibrofolliculoma protein, Birt-Hogg-Dube syndrome protein, FLCN, BHD
Target/Specificity:
This FLCN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-354 amino acids from the Central region of human FLCN.
Antigen Region:
325-354
Antigen Type: Synthetic Peptide
Gene Name: FLCN {ECO:0000303|PubMed:15657874, ECO:0000312|HGNC:HGNC:27310}
Gene ID: 201163
Primary Accession: Q8NFG4
NCBI Accession: NP_653207.1;NP_659434.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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