FLIP (clone AT8B12), anti-human

Description
FLIP, also known as CASP8 and FADD-like apoptosis regulator (CFLAR), contains two death effector domains (DEDs) and a caspase-like domain. FLIP may play a crucial role between cell survival and cell death pathway in mammalian cells and interacts with adapter protein FADD and caspase-8 and -10, and potently inhibits apoptosis induced by all known death receptors DR3 (death receptor 3), TRAIL-R (TNF-related apoptosis-inducing ligand receptor) and TNFR1 (tumor necrosis factor receptor 1).Alternative Names
CASP8 and FADD-like apoptosis regulator isoform 1, CFLAR, CASH, CASP8AP1, CLARP, MRIT, Caspase homolog, Caspase-eight-related protein, Casper, Caspase-like apoptosis regulatory protein, Cellular FLICE-like inhibitory protein, FLAME-1, Inhibitor of FLICE, I-FLICE, MACH-related inducer of toxicityConcentration
1mg/ml (determined by BCA assay)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.