Flotillin 2 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
FLOT2 (Flotillin 2), also known as ESA1 or M17S1, is a protein that in humans is encoded by the FLOT2 gene. Schroeder et al. (1991) isolated a cDNA for an epidermal surface antigen believed to be involved in epidermal cell adhesion. By analysis of a somatic cell hybrid panel and in situ hybridization using the ESA cDNA, the gene was mapped to 17q11-q12 in the region containing the NF1 gene. Bickel et al. (1997) found that mouse Flot2 consistently copurifies with Flot1 and with caveolin-1 in the purification of caveolin-rich membranes. Using a quantitative proteomic analysis of cultured mouse neuronal stem cells, Li et al. (2012) found that palmitoylation and oligomerization of flotillin-2 was abolished in homozygous Dhhc5 mutant neuronal stem cells. The absolute amount of flotillin-2 was not changed in Dhhc5 mutant neurons.

Description:
Rabbit IgG polyclonal antibody for Flotillin-2 (FLOT2) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
ECS-1 antibody, ECS1 antibody, Epidermal surface antigen 1 antibody, Epidermal surface antigen antibody, ESA antibody, ESA1 antibody, Flot2 antibody, FLOT2_HUMAN antibody, Flotillin-2 antibody, M17S1 antibody, Membrane component chromosome 17 surface marker 1 antibody, Membrane component chromosome 17 surface marker 1 homolog antibody, Membrane component, chromosome 17, surface marker 1 antibody, REG-1 antibody, Reggie-1 antibody, Reggie-2 antibody.

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human Flotillin 2 recombinant protein (Position: K169-K344). Human Flotillin 2 shares 100% amino acid (aa) sequence identity with both mouse and rat Flotillin 2.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.