FLT4 Polyclonal Antibody

Background:
This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development. Promotes proliferation, survival and migration of endothelial cells, and regulates angiogenic sprouting.

Research Area: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms:
EC 2.7.10.1, flt 4, FLT-4, FLT4, FLT41, Fms related tyrosine kinase 4, Fms-like tyrosine kinase 4, LMPH1A, PCL, Soluble VEGFR3 variant 1, Soluble VEGFR3 variant 2, Soluble VEGFR3 variant 3, Tyrosine protein kinase receptor FLT4, Tyrosine-protein kinase receptor FLT4, Vascular endothelial growth factor receptor 3, Vascular endothelial growth factor receptor 3 precursor, VEGF R3, VEGFR 3, VEGFR-3, VEGFR3, VGFR3

Immunogen: Synthetic peptide of human FLT4

Swissprot: P35916
Gene Accession: NP891555

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 2.4 mg/mL
Dilution: IF 1: 100-1:500, ELISA 1:5000-1:60000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.