FMO1 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP6994c
Catalog Number: AC-AP6994c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB21944
Applications: WB, IHC-P, FC
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB21944
Applications: WB, IHC-P, FC
Datasheet
Request Information
Background:
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics.
Other Names:
Dimethylaniline monooxygenase [N-oxide-forming] 1, Dimethylaniline oxidase 1, Fetal hepatic flavin-containing monooxygenase 1, FMO 1, FMO1
Target/Specificity:
This FMO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-417 amino acids from the Central region of human FMO1.
Antigen Region:
391-417
Antigen Type: Synthetic Peptide
Gene Name: FMO1 (HGNC:3769)
Gene ID: 2326
Primary Accession: Q01740
NCBI Accession: NP_002012.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics.
Other Names:
Dimethylaniline monooxygenase [N-oxide-forming] 1, Dimethylaniline oxidase 1, Fetal hepatic flavin-containing monooxygenase 1, FMO 1, FMO1
Target/Specificity:
This FMO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-417 amino acids from the Central region of human FMO1.
Antigen Region:
391-417
Antigen Type: Synthetic Peptide
Gene Name: FMO1 (HGNC:3769)
Gene ID: 2326
Primary Accession: Q01740
NCBI Accession: NP_002012.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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