FMR1 antibody (clone 2D4), anti-human
€435.00
In stock
SKU
AC-AT2078a
Catalog Number: AC-AT2078a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
Request Information AC-AT2078a">Request Information
Background:
The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
Other Names:
Fragile X mental retardation protein 1, FMRP, Protein FMR-1, FMR1
Antigen Type:
Recombinant Protein
Gene Name: FMR1 {ECO:0000303|PubMed:8504300, ECO:0000312|HGNC:HGNC:3775}
Gene ID: 2332
NCBI Accession: NP_001172004.1;NP_001172005.1;NP_001172010.1;NP_001172011.1;NP_002015.1
Primary Accession: Q06787
Other Accession: NM_002024
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
Other Names:
Fragile X mental retardation protein 1, FMRP, Protein FMR-1, FMR1
Antigen Type:
Recombinant Protein
Gene Name: FMR1 {ECO:0000303|PubMed:8504300, ECO:0000312|HGNC:HGNC:3775}
Gene ID: 2332
NCBI Accession: NP_001172004.1;NP_001172005.1;NP_001172010.1;NP_001172011.1;NP_002015.1
Primary Accession: Q06787
Other Accession: NM_002024
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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