FMRP FMR1 monoclonal, anti-human, mouse, rat
€455.00
In stock
SKU
AC-ABO13548
Catalog Number: AC-ABO13548
Size: 100 µl
Isotype: Rabbit IgG
Applications: WB, IHC, IF, ICC
Datasheet
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Size: 100 µl
Isotype: Rabbit IgG
Applications: WB, IHC, IF, ICC
Datasheet
Request Information
Description: Anti-FMRP FMR1 Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Protein Function:
Translation repressor. Component of the CYFIP1-EIF4E- FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA- binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly (G), binds moderately to poly (U) but shows very little binding to poly (A) or poly (C)..
Other Names: Fragile X messenger ribonucleoprotein 1, Fragile X messenger ribonucleoprotein, FMRP, Protein FMR-1, FMR1 {ECO:0000303|PubMed:8504300, ECO:0000312|HGNC:HGNC:3775}
Clone Name(s):
Clone: ABAA-6
Subcellular Localization: Cytoplasm. Nucleus. Nucleus, nucleolus.
Tissue Specificity: Highest levels found in neurons, brain, testis, placenta and lymphocytes. Also expressed in epithelial tissues and at very low levels in glial cells..
Gene ID: 2332
Immunogen: A synthesized peptide derived from human FMRP
Calculated MW: 71174
Purification: Affinity-chromatography
Format: Liquid
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Protein Function:
Translation repressor. Component of the CYFIP1-EIF4E- FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA- binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly (G), binds moderately to poly (U) but shows very little binding to poly (A) or poly (C)..
Other Names: Fragile X messenger ribonucleoprotein 1, Fragile X messenger ribonucleoprotein, FMRP, Protein FMR-1, FMR1 {ECO:0000303|PubMed:8504300, ECO:0000312|HGNC:HGNC:3775}
Clone Name(s):
Clone: ABAA-6
Subcellular Localization: Cytoplasm. Nucleus. Nucleus, nucleolus.
Tissue Specificity: Highest levels found in neurons, brain, testis, placenta and lymphocytes. Also expressed in epithelial tissues and at very low levels in glial cells..
Gene ID: 2332
Immunogen: A synthesized peptide derived from human FMRP
Calculated MW: 71174
Purification: Affinity-chromatography
Format: Liquid
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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