FN3KRP Polyclonal Antibody

Background:
A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both enzymes may result in deglycation of proteins to restore their function. Alternative splicing results in multiple transcript variants.

Research Area: Cell Biology, Metabolism, Signal transduction

Synonyms:
EC 2.7.1.- , FLJ12171, FN3K related protein, FN3K-related protein, FN3K-RP, FN3KL, Fn3krp, Fn3krp fructosamine-3-kinase-related protein, FN3X, Fructosamine-3-kinase-related protein, Ketosamine-3-kinase, KT3K, MGC40640, RGD1304570, RP23-293H17.3, Testis secretory sperm binding protein Li 211a

Immunogen: Synthetic peptide of human FN3KRP

Swissprot: Q9HA64
Gene Accession: NP078895

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.56 mg/mL
Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.