FNK Polyclonal Antibody

Background:
Cytokine-inducible kinase is a putative serine/threonine kinase. CNK contains both a catalytic domain and a putative regulatory domain. It may play a role in regulation of cell cycle progression and tumorigenesis. Serine/threonine-protein kinase involved in cell cycle regulation, response to stress and Golgi disassembly. Polo-like kinases act by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates ATF2, BCL2L1, CDC25A, CDC25C, CHEK2, HIF1A, JUN, p53/TP53, p73/TP73, PTEN, TOP2A and VRK1.

Research Area: Signal Transduction

Synonyms:
CNK, Cytokine Inducible Kinase, Cytokine-inducible serine/threonine-protein kinase, FGF inducible kinase, FGF-inducible kinase, FNK, PLK-3, Plk3, PLK3, Polo Like Kinase 3, Polo-like kinase 3, PRK, Proliferation Related Kinase, Proliferation-related kinase, Serine/threonine-protein kinase PLK3

Immunogen: Recombinant protein of human PLK3

Swissprot: Q9H4B4
Gene Accession: BC013899

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-9580/sc-9578/sc-25422