ICOS polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP73896
Background:
Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up- regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up- regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre- activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).
Other Names:
ICOS; AILIM; Inducible T-cell costimulator; Activation-inducible lymphocyte immunomediatory molecule; CD278
Antigen Type: synthetic peptide
Antigen Type: ICOS
Gene ID: 29851
Primary Accession: Q9Y6W8
Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up- regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up- regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre- activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).
Other Names:
ICOS; AILIM; Inducible T-cell costimulator; Activation-inducible lymphocyte immunomediatory molecule; CD278
Antigen Type: synthetic peptide
Antigen Type: ICOS
Gene ID: 29851
Primary Accession: Q9Y6W8
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