Periphilin 1 polyclonal, anti-human, mouse
€470.00
In stock
SKU
AC-AP71848
Background:
Component of the HUSH complex, a multiprotein complex that mediates epigenetic repression. The HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3. In the HUSH complex, contributes to the maintenance of the complex at chromatin (PubMed:26022416). Acts as a transcriptional corepressor and regulates the cell cycle, probably via the HUSH complex (PubMed:15474462, PubMed:17963697). May be involved in epithelial differentiation by contributing to epidermal integrity and barrier formation (Probable).
Other Names:
PPHLN1; HSPC206; HSPC232; Periphilin-1; Gastric cancer antigen Ga50
Antigen Type: synthetic peptide
Antigen Type: PPHLN1 (HGNC:19369)
Gene ID: 51535
Primary Accession: Q8NEY8
Component of the HUSH complex, a multiprotein complex that mediates epigenetic repression. The HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3. In the HUSH complex, contributes to the maintenance of the complex at chromatin (PubMed:26022416). Acts as a transcriptional corepressor and regulates the cell cycle, probably via the HUSH complex (PubMed:15474462, PubMed:17963697). May be involved in epithelial differentiation by contributing to epidermal integrity and barrier formation (Probable).
Other Names:
PPHLN1; HSPC206; HSPC232; Periphilin-1; Gastric cancer antigen Ga50
Antigen Type: synthetic peptide
Antigen Type: PPHLN1 (HGNC:19369)
Gene ID: 51535
Primary Accession: Q8NEY8
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