FOLR2 polyclonal (N-term), anti-human
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In stock
SKU
AC-AP16014a
Catalog Number: AC-AP16014a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31620
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31620
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.
Other Names:
Folate receptor beta, FR-beta, Folate receptor 2, Folate receptor, fetal/placental, Placental folate-binding protein, FBP, FOLR2
Target/Specificity:
This FOLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-44 amino acids from the N-terminal region of human FOLR2.
Antigen Region:
17-44
Antigen Type: Synthetic Peptide
Gene Name: FOLR2
Gene ID: 2350
Primary Accession: P14207
NCBI Accession: NP_000794.3;NP_001107006.1;NP_001107007.1;NP_001107008.1
Other Accession: Q05685; NP_001107008.1; NP_000794.3; NP_001107007.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.
Other Names:
Folate receptor beta, FR-beta, Folate receptor 2, Folate receptor, fetal/placental, Placental folate-binding protein, FBP, FOLR2
Target/Specificity:
This FOLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-44 amino acids from the N-terminal region of human FOLR2.
Antigen Region:
17-44
Antigen Type: Synthetic Peptide
Gene Name: FOLR2
Gene ID: 2350
Primary Accession: P14207
NCBI Accession: NP_000794.3;NP_001107006.1;NP_001107007.1;NP_001107008.1
Other Accession: Q05685; NP_001107008.1; NP_000794.3; NP_001107007.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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